Congenital Aortic Stenosis in Children

نویسندگان

  • Hirofumi Saiki
  • Hideaki Senzaki
چکیده

Congenital aortic stenosis (AS) is caused by abnormal morphological development of the aortic valve. [1, 2] Valvular abnormalities may be accompanied by supraor subvalvular stenosis. The embryogenic process that forms aortic valves begins approxi‐ mately 31–32 days of gestation. Cavity formation in the basal portion of the truncus arteriosus is a key process in the development of the leaflet and sinus of Valsalva, which are important components of the aortic valve. Therefore, incomplete formation of the cavity causes various morphological abnormalities of the aortic valve, including bicuspid valve with or without commissural fusion, tricuspid valve with commissural fusion, monocuspid valve, and myxomatoid leaflet valve (dysplastic valve). The most frequent type of congenital AS is a bicuspid aortic valve, [3] accounting for approxi‐ mately 90% of AS cases.

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تاریخ انتشار 2013